Clinical AI Safety

Resources

The standards behind the curriculum.

Every module points back to primary sources. Start with the standards; the modules translate them into the decisions you will actually face on a Trust.

Primary sources

Start with the documents that govern the work.

  • DCB0129

    Clinical Risk Management: its Application in the Manufacture of Health IT Systems

    NHS Digital / NHS England

    Manufacturer-side clinical risk management and Safety Case requirements.

  • DCB0160

    Clinical Risk Management: its Application in the Deployment and Use of Health IT Systems

    NHS Digital / NHS England

    Deployment-side clinical risk management obligations for NHS organisations.

  • DTAC

    Digital Technology Assessment Criteria for Health and Social Care

    NHS England

    Baseline assessment across clinical safety, data protection, technical assurance, interoperability and usability.

  • PSIRF

    Patient Safety Incident Response Framework

    NHS England

    National framework for responding to and learning from patient safety incidents.

  • ISO 14971:2019

    Application of Risk Management to Medical Devices

    ISO

    The international baseline for risk management in medical devices.

  • BS/AAMI 34971

    Application of ISO 14971 to Machine Learning in AI Medical Devices

    BSI / AAMI

    Guidance on AI-specific failure modes and risk management.

  • MHRA

    Software and AI as a Medical Device Change Programme

    Medicines and Healthcare products Regulatory Agency

    The MHRA's evolving regulatory position on software and AI as a medical device in the UK.

  • ICO

    Guidance on AI and Data Protection

    Information Commissioner's Office

    How UK GDPR applies to AI systems, including DPIA expectations.

Direct links to source documents are deliberately omitted from the MVP: authoritative URLs for several of these standards change without redirect. Search the publisher's site for the current version.

Frameworks at a glance

Twelve frameworks, in one place.

DCB0129

Clinical Risk Management — Manufacturer

Defines the obligations on health IT manufacturers to operate a clinical risk management system and produce a Safety Case.

DCB0160

Clinical Risk Management — Deployment

The deploying organisation's counterpart to DCB0129. Governs how Trusts implement and monitor health IT safely.

DTAC

Digital Technology Assessment Criteria

NHS England's baseline assessment covering clinical safety, data protection, technical assurance, interoperability and usability.

PSIRF

Patient Safety Incident Response Framework

The NHS's approach to learning from patient safety incidents. Replaces the Serious Incident Framework.

ISO 14971

Risk Management for Medical Devices

The international standard for applying risk management across the medical device lifecycle.

BS AAMI 34971

AI Risk Management Guidance

Guidance on applying ISO 14971 to machine learning enabled medical devices, addressing AI-specific failure modes.

MHRA AIaMD

AI as a Medical Device

The MHRA's evolving regulatory approach to software and AI as a medical device in the UK.

UK GDPR / DPIA

Data Protection

Data Protection Impact Assessments where AI processing presents risks to patient rights and freedoms.

NICE ESF

Evidence Standards Framework

NICE's framework for evaluating digital health technologies, including AI-driven tools.

EU AI Act

High-Risk AI Regulation

EU-wide regulation of high-risk AI systems, including health applications. Relevant to UK suppliers operating cross-border.

AMLAS

Assurance of Machine Learning for Autonomous Systems

A structured argumentation-based methodology for assuring the safety of machine learning components.

ECSF

England Clinical Safety Framework

Emerging national framework coordinating clinical safety practice across NHS England.

Disclaimer. Independent educational resource — not affiliated with NHS England or any regulatory body. For educational use only.